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However, downregulation of GPX4 has been demonstrated in lesional skin of psoriatic patients, and treatment with the ferroptosis inhibitor ferrostatin-1 was shown to alleviate psoriasiform inflammation in mice [48]

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The left ventricle was thus divided into three regions: (i) non-ischemic area (blue), (ii) viable tissue within the risk area (red), and (iii) infarcted area (white)